Pre-Implantation genetic diagnosis is a technology that is used to test embryos for severe genetic disorders (including, but not limited to sickle cell anemia, hemophilia, cystic fibrosis and Tay-Sachs), aneuploidy (abnormal numbers of chromosomes), and translocation (chromosomal rearrangements).
To use PGD, conception must occur using IVF or ICSI. Women must take medications that stimulate the ovaries to produce many eggs. Sperm are then added to the eggs in the laboratory. Eggs that fertilize grow and develop into embryos. A single cell is then removed from each embryo. The cells are then sent to a highly specialized genetic testing laboratory for diagnosis. Once testing has been completed, the results are sent back to the doctors at Columbia Fertility Associates. Only unaffected embryos are selected and transferred to the women’s uterus.